Determination of the cellular tropism of viral vectors is imperative for designing precise gene\ntherapy. It has been widely accepted that transduction of hepatocytes using adeno-associated virus\nserotype 8 (AAV8) is a promising approach to correct inborn errors in neonates, but the type of neonatal\nhepatic cells transduced by AAV8 has not been thoroughly investigated. To address this question,\nwe used a reporter mouse that carries Cre recombinase (Cre)-inducible yellow fluorescent protein\n(YFP). Our analysis primarily focused on cholangiocytes, given their pivotal roles in normal liver\nfunction and disease. We treated................
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